Reversible Neonatal Cholestasis Following In Utero Exposure to Valproic Acid
نویسندگان
چکیده
منابع مشابه
Neonatal outcomes following in utero exposure to buprenorphine/naloxone or methadone
OBJECTIVES To study neonatal outcomes following buprenorphine/naloxone and methadone exposure during pregnancy. METHODS This study is a retrospective review of clinical and demographic information of 58 infants whose mothers were treated with buprenorphine/naloxone and 92 infants whose mothers were treated with methadone for opioid dependence during pregnancy. RESULTS Gestational age, birth...
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Abnormalities in anatomy and function of the cranial nerve motor nuclei and brain stem structures have been demonstrated in some people with autism and can be modeled in rats by exposure to valproic acid (VPA) during very early nervous system developmental stages (neural tube closure). The aim of this study was to investigate if VPA will have an impact on nociception in rats because of reported...
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Valproic acid (VPA) is among the most teratogenic of commonly prescribed anticonvulsants, increasing the risk in humans of major malformations and impaired cognitive development. Likewise, rats exposed prenatally to VPA exhibit a variety of neuroanatomical and behavioral abnormalities. Previous work has shown that pyramidal neuron physiology in young VPA-exposed animals is marked by two strong ...
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ژورنال
عنوان ژورنال: McGill Journal of Medicine
سال: 2020
ISSN: 1715-8125
DOI: 10.26443/mjm.v2i2.563